pentyl[1-(3,4-dihydroxy-5-methyl-tetrahydrofuran-2-yl)- 5-fluoro-2-oxo-1H-pyrimidin- 4-yl]aminomethanoate

Antacids
May increase capecitabine levels.

Cimetidine, metronidazole
May increase serum concentrations of fluorouracil and potentially increase toxicity.

Fluorouracil
Drug interactions have been reported with fluorouracil, the principal active metabolite of capecitabine.

Leucovorin
May enhance GI toxicity of fluorouracil.

Levamisole
Risk of hepatotoxicity may be increased by coadministration with fluorouracil.

Phenytoin
Levels may be elevated by capecitabine, increasing the risk of adverse reactions.

Warfarin
May alter warfarin's effects, increasing the risk of bleeding.