| 結構式 |
|
1 ml contains:
Zinc chloride 521 μg
Copper chloride 2 H2O 53.7 μg
Manganese chloride 4 H2O 3.60 μg
Sodium selenite anhydrate 4.38 μg
Sodium fluoride 126 μg
Potassium iodide 1.31 μg
|
| UpToDate |
UpToDate 連結
|
| 適應症 |
|
|
To cover basal trace element needs for neonates and children receiving total intravenous nutrition.
|
| 用法用量 |
|
Must be diluted.
1 ml Peditrace per kg of body weight per day for infants and children weighing up to 15 kg. For children weighing 15 kg or more, a daily dose of 15 ml Peditrace covers the basal need of trace elements. The infusion duration should be at least 8 hours.
|
| 藥動力學 |
|
|
Copper and manganese are normally excreted via the bile, whereas selenium and zinc (especially in patients receiving intravenous nutrition) are mainly excreted via the urine.
|
| 副作用 |
|
|
No side effects related to the trace elements in Peditrace have been reported.
|
| 禁忌 |
|
|
Wilson’s disease.
|
| 注意事項 |
|
Peditrace should be used with caution in patients with impaired biliary and/or renal function, in whom the excretion of trace elements may be significantly decreased.
Peditrace should also be used with caution in patients with biochemical or clinical evidence of liver dysfunction (especially cholestasis). Trace element levels in plasma must be monitored in patients with cholestatic liver disease and renal insufficiency. If treatment lasts more than 4 weeks, manganese levels must be checked.
If intravenous nutrition is administered for a prolonged period of time (month), plasma levels of trace elements should also be monitored.
|
| 警語 |
|
Additions must be made aseptically.
Compatibility Up to 6 ml Peditrace can be added to 100 ml Vaminolac, Vamin 14 g N/l electrolyte free or glucose solution 50-500 mg/ml. Data on addition to mixtures in phthalate-free bag and for addition to TPN solutions is available upon request from the manufacturer.
|
| 藥品保存方式 |
|
|
Store at a maximum of 25°C. Do not freeze.
|
