Neomycin：unknow

1.腸管感染症：成人一日八顆，分四次服用。

2.腸管手術前處理時，成人一日16粒，每日分四回服用，連續服用1-3天。

Absorption：Poorly absorbed from the GI tract (3%).

Distribution：Small amount absorbed is rapidly distributed to the tissues. Removed by dialysis.

Elimination：Small fraction absorbed is eliminated by the kidney. The unabsorbed portion (97%) is eliminated unchanged in the feces.

Aminoglycosides, polymyxins, neurotoxic or nephrotoxic agents
Neomycin ototoxicity or nephrotoxicity may be enhanced.

Anticoagulants (eg, warfarin)
May increase the anticoagulant effects by decreasing vitamin K availability.

Digoxin, fluorouracil, methotrexate, penicillin V, vitamin B-12
Intestinal absorption of these agents may be inhibited by neomycin.

Potent diuretics (eg, ethacrynic acid, furosemide)
When administered IV, diuretics may enhance neomycin toxicity by altering the concentration in serum and tissue.