Absorption Injection T max is 16 to 25 min.
Nasal Rapidly absorbed. T max is 31 to 39 min. Bioavailability is approximately 3%.
Distribution Calcitonin does not cross the placenta.
Metabolism Rapidly metabolized to inactive fragments, primarily by the kidneys but also in the blood and peripheral tissues.
Elimination A small amount is excreted in the urine. The t ½ is 43 min.
Duration 5 to 8 days (hypocalcemic effect after chronic dosing).
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