2-(16-acetyloxy-3,11-dihydroxy-4,8,10,14- tetramethyl- 2,3,4, 5,6,7, 9,11,12, 13,15,16- dodecahydro- 1H-cyclopenta [a]phenanthren-17-ylidene) -6-methyl- hept-5-enoic acid

Protein binding: 97%

Metabolism: Hepatic, to multiple metabolites

Half-life elimination: 5-6 hours

Time to peak, serum: Oral: 2-4 hours

Excretion: Feces (~100%, via bile)

Penicillins: Fusidic acid may decrease the therapeutic effect of penicillns; administer the pennicillin at least 2 hours before fusidic acid.

Rifampin: Concurrent administration may increase the risk of jaundice.

1.由肝臟代謝,因此膽道異常者或併用其他類似排泄途徑之抗生素如Lincomycin或rifampicin之患者,應定期檢查肝功能。

2.患有黃疸酸中毒或嚴重急病的新生兒在服用本品時應留意。