1. 成人：
a. 精神病：口服─每天30～20mg。
b. 噁心/嘔吐：口服─每4～6小時1次，每次10～25mg。
c. 手術前的鎮靜：口服─25～50mg。
d. 吡咯紫質沈著症：口服─每天3～4次，每次25～50mg。
e. 呃逆：口服─1天3～4次，1次25～50mg。

2. 孩童：口服─1天2～4次，1次0.55mg/kg。

Alcohol and other CNS depressants
May cause increased CNS depression and may precipitate extrapyramidal reaction.

Anticholinergics
May reduce therapeutic effects of and increase anticholinergic effects of chlorpromazine; may lead to tardive dyskinesia.

Barbiturate anesthetics
May increase frequency and severity of neuromuscular excitation and hypotension.

Beta-blockers
May result in increased plasma levels of beta-blocker and chlorpromazine.

Cisapride, sparfloxacin
The risk of life-threatening cardiac arrhythmias, including torsades de pointes, may be increased.

Epinephrine, norepinephrine
Actions of these drugs may be decreased or reversed.

Guanethidine
The hypotensive effect of guanethidine may be inhibited.

Lithium
May cause disorienting unconsciousness and extrapyramidal effects.

Meperidine
May result in excessive sedation and hypotension.

Metrizamide
Risk of seizure may increase.

Paroxetine
Plasma levels of chlorpromazine may be elevated, increasing the risk of adverse reactions.